The side effects of the drug are systematized relative to each of the systems of organs, depending on the frequency of occurrence, using the following classification: Very often - more than 1/10; often more than 1/100, less than 1/10; more infrequent - more than 1/1000, less than 1/100; rarely - more than 1/10000, less than 1/1000; Very rarely, including single messages - less than 1/10000.
The adverse reactions with the use of Orlistate occurred mainly on the part of the tract and were due to the pharmacological effect of Orlistat, which prevents the suction of food fats.
Very often there were such phenomena as oily discharge from the rectum, the release of gases with a certain amount of separated, imperative calls for defecation, steatheree, the increase in defecation, liquid chair, flatulence, pain or discomfort in the stomach. Their frequency increases with increasing fat content in food.
Patients should be informed about the possibility of adverse reactions on the part of the tract and teach, how to eliminate their observance of the diet, especially in relation to the amount of fat contained in it. The use of a low fat dieting reduces the likelihood of side effects by the tract and thereby help patients control and regulate consumption of fats.
From the head of the gastrointestinal tract: often - "soft" chair, pain or discomfort in the rectum, incontinence of feces, bloating, teeth defeat, leaning gums.
Other unwanted reactions: Very often - headache, infection of the upper respiratory tract, influenza; Often - infections of the lower respiratory tract, urinary tract infection, dysmenorrhea, anxiety, weakness.
In patients with type 2 diabetes, the nature and frequency of undesirable phenomena were comparable to those in individuals without sugar diabetes with excess body and obesity. The only additional side effects in patients with type 2 diabetes were hypoglycemic states that occurred with a frequency of more than 2% and incidence of at least 1% compared with placebo (which could arise as a result of improving the compensation of carbohydrate metabolism), and often - bloating.
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