Pregnancy is a wonderful, and at the same time a difficult period in the life of a woman who is characterized not only by joy and pleasant troubles, but also some health difficulties. It is difficult to get rid of various physical troubles, because it doesn't really want to take medicine because of the concern to harm the baby. In this article, we will talk about the safe preparation of the candlelight of papaverine hydrochloride during pregnancy.
Papaverin refers to the group of spasmolitics. It is able to reduce blood pressure in the arteries and remove the tension that occurs in the smooth muscles of the internal organs. Reception of the drug in large quantities has a soft soothing effect on the nervous system, reduces the pace of heartbeat. The medication comes on sale in the form of ampoules with a solution for injection, tablets and candles. You can only make injections in the hospital, then how to use candles with papaverine during pregnancy, a woman can and at home. This is a very convenient form of a drug that does not require medical control.
the most common diagnosis requiring the use of this medication, the fesce of the walls of the uterus. This rather unpleasant phenomenon increases the risk of premature birth and miscarriage. With a tone of the uterine candles, Papaverin give the opportunity to a few "relax" and provide the kid of all the conditions for normal development. Regular use has a positive effect on a psycho-emotional state of pregnant.
There is an opinion, allegedly, this drug is extremely undesirable to be used during the kid tool. However, such information is absolutely groundless, which there are appropriate scientific and medical research. According to medical observations, all women who used Papaverin candles became the mothers of healthy, strong and full-fledged children. Experience shows that this drug not only does not harm the fetus or pregnant, but also makes it possible to normally and fragile the child, without fear of miscarriage due to the tone of the uterus.
Papaverin hydrochloride is a spasmodic drug, that is, the mechanism of its action lies in the relaxation of smooth muscle cells. It affects vessels and all organs and systems in which there is a smooth musculature. This is one of the few drugs that is widely used for the treatment of pregnant women. It not only does not have a negative impact on the growth and development of the baby, but in the presence of testimony also reduces the tone of the uterus and improves the blood flow in the royal and placental system.
Papaverin is produced in the form of rectal candles, tablets and injection solutions. The choice of dosage form is determined depending on the indication and degree of severity of symptoms. The duration of treatment can be from several days to 2 - 3 weeks, and sometimes more:
Despite all positive aspects, you still do not need to abuse the admission of papaverine. After all, as well as any medicine, he has side effects that pregnant people can manifest themselves more often than those of the rest of the people.
Reliable data on the use of papaverin in women during breastfeeding is not. Therefore, if necessary, the treatment of this drug is better to overcome the child from the chest, and after recovery, resume breastfeeding.
Pharmacological propertiesFarmakokineticsBastro and completely absorbed. Binds with plasma proteins by 90%. Easily passes through histohematic barriers. Biotransformation is subject to biotransformation. The preparation half-life is 0.5-2 hours. Examped by the kidneys, mainly in the form of metabolites.
PharmacodynamicApaperin hydrochloride is a mullopic antispasmodic, hypotensive agent. Inhibits phosphodiesterase and causes the accumulation of cyclic 3 ', 5' of adenosine monophosphate in the cell and decrease in the calcium level. Reduces the tone of smooth muscles of internal organs and vessels. Causes the expansion of the arteries, contributes to an increase in blood flow, including cerebral. In large doses reduces the excitability of the heart muscle and slows down intracardiac conductivity. When used in medium therapeutic doses, papaverin practically does not have a central nervous system.
The method of use and doser is subcutaneously or intramuscularly administered 1-2 ml of 2% solution for injection. Dirty (very slowly!) Impact 1 ml, pre-diluating 10 to 20 ml of isotonic sodium chloride solution. Aximum doses for adults: one-time 0.1 g (5 ml), daily 0.3 g (15 ml). La elderly patients initial one-time dose no more than 10 mg (0.5 ml). For children aged 1 to 12 years, the maximum one-time dose is 0.2-0.3 mg / kg.
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Almost every pregnant woman is familiar with the term "hypertonus of the uterus". This phenomenon is quite common, but the norm is not the norm and represents the danger to the course of the pregnancy up to its premature interrupt. Fortunately, modern medicine has a large arsenal of medicines that can effectively remove the voltage muscles. Among them are long-known and widely used Papaverin candles. Like any drug, this drug is possible to apply a pregnant woman only to the appointment of a doctor, but every future mother is useful to know all the nuances of its impact on the body and the basic rules of use.
Although the papaverine hydrochloride is actively appointed by the gynecologist with pregnant women for both outpatient and stationary treatment, instructions for the drug interprets its use during the gestation period (tooling the child) ambiguously. According to the manufacturer presented by recommendations, the safety of the use of papavmer is not established by future mothers. Of course, this circumstance in combination with the prescribed appointment of a doctor will be confused by a woman who is consciously related to the use of drugs during pregnancy.
It should be noted that clinical studies of the effectiveness and safety of the use of the drug Papaverin in pregnant women were not really conducted. Nevertheless, the long-term practice of the use of Papaverin is completely unequivocally indicative of its positive impact on the course of pregnancy and at the same time about full safety for the fetus.
Papaverin is able to have a positive effect and under constipation, if they are caused by muscle spasm (spastic constipation). In atonic constipation, which is caused by a decrease in the tone of the intestinal muscles, Papaverin will only aggravate the situation.
Hyperthonus of the uterus can be called one of the frequent and most dangerous problems during pregnancy. To eliminate, doctors use antispasmodic preparations, for example, "Papaverin". If the situation requires immediate assistance, and the risk of miscarriage is very high, the future mother is prescribed such a medicine in injections.
The medicine itself is a transparent sterile solution, which is spilled in 2 ml ampoules. It is most often colorless, but the greenish-yellow tint is also the norm. The drug is sold in cardboard bundles of 5 or 10 ampoules.
The active substance of this solution is papaverine hydrochloride at a concentration of 2% (each milliliter of drugs contains 20 mg), and the auxiliary substances are methionine, sterile water and trilone b or editat of the dynamody.
This situation in the early periods is dangerous in what can lead to miscarriage, and Hyperthonus in 2 and 3 trimester harms the development of the baby (interferes with the flow of nutrients) and may cause premature birth.
Although the instructions for the solution it is not indicated that such a drug can be applied during pregnancy, gynecologists prescribe "Papaverin" injections for several decades and note their high efficiency.
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Chronic constipation are the most common pathology of the gastrointestinal tract during pregnancy. The constipation not only worsen the quality of life of women, but also contribute to the development of the intestinal dysbacteriosis, activation of the externalopathogenic microflora, the translocations of the microbes and their toxins through the intestinal wall, decrease in immunity, which is the immediate cause of serious complications during pregnancy, childbirth and postpartum period. The article discusses the causes of constipation and their treatment.