HCG - hormone, refers to gonadotropic human hormones, differs from them an amino acid sequence. His appearance in the blood of a woman means she is pregnant. This hormone begins to produce a cloth of chorion, as soon as the embryo attachment to the mucous membrane of the uterus occurs. For a certain period, the formation of the placenta is underway, it supports the desired level of estrogen and progesterone. These hormones are responsible for pregnancy within the norm. This analysis most accurately determines pregnancy at the very beginning of its development. It is most often used with vitro incense.
Deliver blood to the hormone follows your cycle schedule, on 10 day after allowable ovulation, or on the first day of delay. The delivery in earlier deadlines is not always justified, since errors occur in the definition of the hormone level. It is necessary to donate the blood on an empty stomach, in the morning. It is impossible to donate blood after severe physical exertion, when treating hormonal drugs. The result will be ready in a few days.
The level of hCG in the first week after conception is growing rapidly. And starting from 9 weeks of the placenta, which has already formed, takes on maintaining a normal hormonal background in the body of a woman. At the same time, the chorionic gonadotropin of a person is responsible for the normal functioning of the placenta.
The objectives of determining the level of hCG in the blood, as well as the general trend of changing this indicator during pregnancy, we described in the article . Now let's discuss in detail on the CHG standards for weeks that help identify pathology of pregnancy or confirm its normal course. Immediately warn: maintaining pregnancy, including the purpose of the tests and their interpretation is a qualified physician.
To be more convenient to navigate in the HCG indicators for weeks, the standards are taken to submit in the form of a table. Note, in the first table, the term of pregnancy is an obstetric, that is, the weeks are counted from the first day of the last menstruation. The laboratory frequently give reference values for the embryonic period, you will see such a table just below.
In the Medical Center "Seven Clinics" you can pass "blood test for hCG" with a discount for 288 rubles. We are located in the Northwest area (in the North) at: Baivel, 14 (MKR-N Alexandrovsky,).
The level of hCG in the blood begins to rise in the first days after the fertilization of the egg. Approximately 5% of pregnant women, the HCG level rises already on 8 day after conception, and most women have from 11 days. If you do not know the exact date of conception, then the blood test on hCG is recommended to be passed after 3-4 weeks after the first day of the last menstruation (with a delay in several days).
Often, gynecologists are recommended to pass the blood test on HCG not one, but twice with an interval in a few days. Repeated analysis is recommended to hand over in the same laboratory as the first. If the woman is pregnant, the level of hCG will rise at 1.5 - 2 times compared with the previous analysis. If there is no pregnancy, the level of hCG will remain the same or drop.
hgch or beta-hgch or common hCG - human chorionic gonadotropin is a hormone formed during pregnancy. HCG is formed by the placenta, which feeds the embryo after fertilization and implantation (attachment to the wall of the uterus).
hCG partially penetrates through a placental barrier. The level of hCG in newborns approximately 1/400 from the level in the motherboard. And approximately 10-50 MME / ml at birth. Half-life - 2-3 days. Thus, in 3 months of life, the level of newborns corresponds to the norm of the HCG of an adult.
On average, the doubling of the HCG level occurs every 36-72 hours. The level of hCG reaches its peak on a period of 9-11 weeks of pregnancy (from the date of the last menstruation) and further decreases to 15 weeks of pregnancy, remaining unchanged over the remaining period of pregnancy. In 85% of cases, the level of hCG in the early periods increases twice all 48-72 hours. As the pregnancy develops, the doubling time of the HCG level increases to 96 hours.
After reaching the level of HCG 1000 - 2000 mm / ml, a fruit egg may be visualized with ultrasound examination. Since the HCG level has greater variability, and the date of conception can be erroneous, the period of pregnancy is determined by the ultrasound or according to ECO, but not by hCG. A single definition of hCG is not enough, as it is important to assess the dynamics of hormone growth every 48-72 hours.
It is necessary to repeat the analysis on HCG after 1-2 days, perhaps the pregnancy occurred later than the expected period. If the level of hCG does not grow, it is necessary to look for other causes of menstruation delay.
The so-called "biochemical pregnancy" is a state at which an increase in hCG was discovered above the norm, but pregnancy did not continue to develop. The HCG level in this case increases slightly, and then in a short time it decreases to zero values.
Emascus pregnancy is a pregnancy at which the fruit egg is outside the uterine cavity. With ectopic pregnancy, pain can occur at the bottom of the abdomen, bleeding. The level of hCG with an ectopic (ectopic) pregnancy can increase not so quickly and not as much as with a normally developing uterine pregnancy. However, the low level of hCG does not allow to make such a conclusion unequivocally. Starting from the level of hCG 1000 MME / ml, a fruit egg can be detected in the uterine cavity. At the level of hCG 2000 mm / ml and the absence of a fruit egg in the uterus cavity with an ultrasound probability of ectopic pregnancy is significant.
In the first trimester of pregnancy, HCG supports a yellow body and stimulates the production of progesterone hormones and estrogen necessary to maintain pregnancy. This happens until the fruit fetter system starts to form the necessary hormonal background independently.
HCG begins to be produced already on 6-8 days after fertilization. In the first weeks of pregnancy, its level doubles approximately every 2-3 days (from 48 to 72 hours). The increase in the level of HCG by 60% in two days is also considered the norm. As the term of pregnancy increases, the growth rate of the HCG level falls. Upon reaching the level of 1200 U / l, the hCG level is usually doubled every 3-4 days (from 72 to 96 hours). After 6000 units / l doubling occurs on average every 4 days (96 hours). After 8-9 obstetric weeks of pregnancy (from conception ~ 6-7 weeks), HCG ceases to grow and begins to slowly decrease.
Therefore, for the accurate estimate of the level of hCG, tests on beta subunit of this hormone (beta-hCG) are used. In test strips for rapid diagnostics, pregnancy is used, in most cases, a less specific test for hCG.
HCG (HCG) is translated as chorionic human gonadotropin and is a significant biomarker to confirm the fertilization and detection of pathologies during gestation. HCG during pregnancy in the early time is detected in the urine and serum.
The significance of the HCG indicator during pregnancy is that this substance not only confirms the conception, but also determines the possibility of miscarriage and serious embryo pathologies. Causes for examination:
Hormonal background Women influences the state of her health throughout life. HCG (human chorionic hormone) is constantly produced by a permanent hypophism, however, its reinforced products occurs during pregnancy. Based on how the level of hCG, the days and weeks of pregnancy, one can judge how this physiological process flows.
Horion hormone human (HCG) is produced by both women and men. In the body of a woman produces a pituitary. In the men's organism, the synthesis of hCG occurs in the testicles. Its concentration is insignificant and never bes above five miliemternational units in one millilitress of blood.
HCG in its structure is a glycoprotein with a rather large molecular weight. It consists of two unequal particles in its value: α and β. α Subunit is available not only in hCG, but in other gonadotropic and thyroid hormones. The component, which differs in HCG from other gonadotrops is its β substance. Due to it, such properties of the chorionic hormone are manifested as immune specificity and biological activity.
The biological activity of hCG is similar to that in the follicularity and luteinizing hormones. It is able to bind to both varieties of receptors to gonadotropins. HCG exhibits more pronounced luteinizing activity than follicle-sustimulating.
After conception, the hCG begins to be produced not only by the pituitary gland, but also the placenta. The activity of placental hCG is much stronger than the pituitary. It is he who contributes to the fact that pregnancy remains. Normally, the yellow body formed on the site of the burst follicle is resolved after two weeks. If the egg fertilization occurs and its implantation occurs, then from the first days of pregnancy, the sycitiotrophoblast begins to produce HCG, which does not allow a yellow body.
It continues to function over two weeks and synthesizes progesterone and estrogen supporting pregnancy. Only after the placenta becomes capable of producing these hormones itself, the need for yellow body disappears, and it itself is eliminated. HCG has the ability to stimulate the synthesis of the yellow body of a minor number of estrogen and weak androgens.
It also has an immunosuppressive effect, which allows pregnancy to preserve. Since HCG causes the physiological hyperplasia of the adrenal cortex, then during pregnancy in the blood of the woman, the number of corticosteroid hormones increases. Glucocorticoids increase the stability of a pregnant woman to stress, which causes pregnancy itself. In addition, they are powerful immunosuppressors, which does not allow the fetus to rejust.
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