MAZ ONCOCITOLOGY | Medical Center "President-Med"

In the Russian Federation, cervical cancer (RSM) occupies the 5th place among oncological diseases and the 2nd place as the cause of death from cancer in women up to 45 years. In Russia, 12,000 women fall in RSM annually, while the increase in the incidence of RSHM among young women aged less than 29 years is noted.

• do not urinate 3-4 hours before the smear fence;
• do not take antibacterial drugs and antiseptic agents before going to the doctor.

Taking a smear on the flora from the urethra is an analysis that is prescribed by men with urological examination. With the help of a subtle probe, the doctor collects biological material - separated from the urethra. It is placed on the glass and sent to the laboratory, where they are viewed under the microscope.

What allows you to reveal the study?

Analysis of the smear helps determine from which the microflora of the urethra consists, and identify signs of inflammation or infection. From how sharp and the inflammatory process is underway, the number of cell elements in the urethra separated.

What can be detected in a smear? First of all, elements in the level of which can be judged by the health of microflora: leukocytes (normally up to 15 units in the field of view), the cells of the flat epithelium is a layer lining the urethra and sticks. A large number of leukocytes speaks of an inflammatory process, and the lack of epithelium cells - about atrophy epithelial cells. Wands are the only microorganisms that must be present in the smear. If there are other microorganisms as part of microflora, this may indicate the presence of infection. Among the pathogens can be yeast mushrooms (sign of candidiasis, or thrush), trichomonas, gonococci - pathogens of gonorrhea.

The study helps the doctor to diagnose such diseases of the genitourinary system as non-flower urethritis, gonorrhea, trichomoniasis. Also, with the help of this analysis, the doctor may be determined by sexually transmitted infections in the early stages, and prescribe treatment, preventing the risk of developing complications.

Preparation for the procedure

Urethra is an organ that is washed with urine. Usually epithelium, leukocytes, microorganisms and pathogens are washed away from the surface of the urethra during urination, and after a few hours their quantity is restored. Therefore, that the survey results are as accurate as possible, the patient is recommended:

The test is designed for women of reproductive age (18-45 years). In girls and women in Menopause, the composition of the vagina microflora differs from those in women of reproductive age, which is why the test results may be distorted.

According to the results of comparative studies, the menstrual cycle phase at the time of the delivery of biomaterial for analysis does not affect the result of the study. The study is not recommended during menstrual bleeding.

The study is recommended to conduct no earlier than 4 weeks after the last reception of antibacterial or antiseptic drugs. On the eve of the taking of the smear, it is not recommended to spend the vagina.

All test components have passed clinical validation with respect to traditional research methods that are "gold standards" of the diagnosis of individual urogenital infections. For example, high sensitivity and specificity of the diagnosis of trichomoniasis, gonococcal and chlamydial infections, as well as infections caused by mycoplasma genitalium, are confirmed in Laboratory Reference and Research Branch, Division of Std Prevention, CDC, Atlanta, USA. Detailed information on clinical validation of the Florocenosis test is available.

Yes, the test can be used not only to determine the causes of itching, burning, pathological discharge from the vagina, but also to identify the so-called "hidden" infections, which, according to various authors, are 30-50% of cases urogenital infections.

Yes, this is one of the main indications for the purpose of this test. Before the adventury of pregnancy, it is recommended to conduct a survey for bond pathogens and clinically significant conditionally pathogenic microorganisms. The state of pregnancy is associated with an increased risk of developing dysbiotic states (bacterial vaginosis, vulvogenic candidiasis, etc.), which are associated with adverse pregnancy outcomes.

Test Florocenosis is performed by PCR method in "Real Time". The essence of the PCR method is to significantly increase the number of specific DNA fragments of the detected microorganisms and detection of this process to increase fluorescence of the reaction mixture. Since DNA is an integral and unique part of each living organism, "confuse" or "skip" its analytical system is almost impossible. That is why the PCR method has such high accuracy in the diagnosis of infections.

Bondal pathogens require treatment, regardless of whether the pathogen is detected. In the case of infections caused by conditionally pathogenic microorganisms, the decision on the need for treatment is taken on a totality of data, among which the density of the separation of the mucous pathogen is playing a special role (along with the history and complaints of complaints). Therefore, NCMT infections in the Florocenosis test are detected in a qualitative format, and all others are in quantitative.

no earlier than 4 weeks, so. It is during this time that the remnants of DNA of the dead microorganisms are completely eliminated from the urogenital tract. The waiting time of the control test can be reduced to 2 weeks if a control study is carried out by the method that reveals the RNA of the pathogens, which is mainly in living microorganisms. The study by NASBA is available for trichomoniasis, gonococcal and chlamydial infections, as well as infections caused by mycoplasma genitalium.

21st century is the time of freedom, including in sexual relationships. But here there are its consequences. A frequent selection of a partner, sexually transmitted infections, infinite drug contraception leads to a violation of the immune and hormonal background. As a result, as statistics shows, each second woman is confronted with the diagnosis of the erosion of the cervix. If you do not pay attention to these problems in time, it can bring to the most terrible consequences.

Damage can be the basis for formation on the mucous membrane of the cervix of the rings, which will turn into erosion. However, there are other reasons that may cause this female disease - infectious inflammatory processes, STDs, disruption of microoflor.

This statement is not true. The erosion of the cervix can be detected in young girls if the vaginal microflora failure (dysbiosis or vaginal dysbiosis) occurs. Similar disorders of microflora are called pseudo-erosions and need treatment.

erosion by mistake is often ranked towards those diseases, which can be found only when examining the gynecologist. But this is true only for erosion, which has become a consequence of mechanical damage. In most cases, erosion occurs simultaneously with the infectious process for which the allocation of various nature is characteristic. The discharge may be accompanied by the drains when urination, burning, irritation, itching, can be muddy mucous, yellowish, bloody, whitish. All this signals that you need to urgently apply for help to the gynecologist.

Any launched damage in the region of the uterus can be the basis for the development of an oncological disease, especially against the background of an infectious disease. The virus can be broken into the cell and damage it at the genomic level, which will become the basis for the occurrence of atypical diseases. Therefore, if you have revealed erosion, you need to immediately take care of it. The smaller the process is running, it will be easier to cure it.